iGeneTech Multi-Pathogen Detection Solution
During June to August, the Northern Hemisphere enters a hot and humid summer. The continuously rising temperature accelerates the rate of food spoilage and deterioration. Meanwhile, the increase in activities such as street night markets and outdoor dinners significantly raises the risk of people coming into contact with contaminated food and water sources, thereby greatly increasing the chance of infection with pathogenic bacteria such as Salmonella and diarrheagenic Escherichia coli.
At the same time, environmental sanitation issues caused by increased rainfall also provide favorable living conditions for the spread of pathogens like Vibrio cholerae and Norovirus. Infants, the elderly, and people with weak immunity have become key vulnerable groups for infection.
On June 13, 2025, a provincial Center for Disease Control and Prevention (CDC) in China issued an emergency notice, explicitly requiring all sentinel hospitals to strictly follow the principle of territorial management and fully implement sentinel surveillance tasks for diarrhea syndrome.
The notice specifically emphasized that network laboratories should conduct multi-dimensional and high-precision pathogen detection on submitted samples, covering 13 types of bacteria (such as Salmonella, Shigella, Vibrio cholerae, etc.), 5 types of viruses (including Rotavirus, Norovirus, Adenovirus, etc.), and 3 types of parasites (such as Entamoeba histolytica, Giardia, etc.). This initiative aims to accurately grasp the dynamics of the pathogen spectrum and provide a scientific basis for epidemic early warning, clinical diagnosis and treatment, and the formulation of prevention and control strategies.
To promptly grasp the pathogen spectrum, characteristics and trends of diarrhea patients and enable simultaneous multi-pathogen detection, iGeneTech has launched multiple whole-genome capture kits for diarrhea syndrome-related pathogenic microorganisms. These kits obtain the whole-genome sequences of pathogenic microorganisms without cultivation, helping CDCs achieve "accurate detection and early treatment".
Leveraging its proprietary TargetSeq® liquid-phase probe hybridisation capture technology, iGeneTech designs diverse specific probes using multiple strain sequences from the NCBI database. These probes cover multiple variants of pathogenic microorganisms, accommodate their emerging mutations, and prevent missed detections.
1. Probe Indicator Data
2. Mapping Rate, Coverage Rate, and Uniformity Results of Partial Pathogen Test Samples
(1) Representation of Rotavirus Actual Measurement Data
(2) Representation of Norovirus Actual Measurement Data
(3) Representation of Vibrio cholerae Actual Measurement Data
Worry-Free Full-Process Detection
The pathogenic microorganism whole-genome capture kits have sufficient stock. Combined with magnetic bead-based extraction kits, RNA pathogen library construction & capture kits, and DNA pathogen library construction & capture kits, they enable seamless connection from sample to data. The kits support batch processing with automated liquid handling workstations and are compatible with multiple high-throughput sequencing platforms to meet diverse scenario requirements.
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