AIExome® Human Exome Panel V5–Tumor is a version of AIExome® V5 specifically designed to detect tumor related mutations. In addition to the superior coverage of CDS region as AIExome® V5, AIExome® V5–Tumor also covers important fusions, MSIs, HLA, mtDNA regions and tumor related genes.
| Panel Number | T1248V1hg38T |
| Technical Platform | TargetSeq® Hybridization Capture Sequencing |
| Coverage Size | 35.26 Mb |
| Reference Database | CDS (RefSeq & refGene)*, MANE, CCDS |
| Reference Genome | GRCh38 (hg38) and GRC |
| Coverage | CDS, tumor-associated gene with high depth, fusion region, MSI locus, 200K backbone, HLA 15 gene, mtDNA |
| Storage | ≤-20℃ |
| Sequence Platform | Illumina / MGI |
| Recommend Sequencing Read Length | PE150 |
| Recommend Sequencing Data Size and Depth | 20Gb/sample, with WES region 100×, and hot regions 400× |
Covering over 99.9% of the CDS regions in major genetic databases.
MSI and TMB analysis enabled.
Increased probe density in regions of 641 tumor-related genes (especially mutation hotspots) to avoid missing detection of these key genes.
Upgraded TargetSeq One® v3.0 kits and workflow for easier use and more reliable experiments.
Compatible with automated workflow to reduce manual operation and human errors.
Stable data reproducibility across different NGS platforms, with excellent data performance and outstanding cost-efficiency.
AIExome V5-Tumor, based on covering over 99.9% of protein-coding regions from databases such as CDS (RefSeq & refGene)*, MANE, and CCDS, additionally includes detection regions for Fusion, MSI, HLA, HRD, and mtDNA. It achieves multi-variant detection needs in a single probe tube and one-time testing, truly realizing All-in-one.
The coverage rate of coding sequence (CDS) regions in AIExome V5-Tumor across multiple databases significantly outperforms competing products.
AIExome V5-Tumor features a unique depth adjustment technology that increases the depth of tumor-related regions by approximately 4 times compared to other exonic regions. Specifically, with 10 Gb of data and an average depth of 100× across the whole exome region, the depth for tumor-related genes can reach approximately 400×.
While saving data volume and increasing depth, the high-depth tumor-related regions enable accurate detection of low-frequency mutations.
| Product Name | Set | Cat. No |
| AIExome® Human Exome Panel V5-Tumor | 24 rxn | PH2007385 |
| 96 rxn | PH2007382 |
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