Core Genes Fusion RNA Panel - iGeneTech Bioscience Co., Ltd.

Overview

Advantages

Performance

Ordering Info

Resources

Overview

This product has selected the coding regions of transcripts of 90 common major fusion genes in tumors and the UTRs (untranslated regions) of some genes for probe design. It supports the detection of fusion, variation, and gene expression information at the RNA level, providing clinical reference for tumor diagnosis and classification, prognosis evaluation, and recurrence monitoring.

Product Specifications

Technical Platform	TargetSeq® Hybridization Capture Sequencing
Coverage Size	582.6 kb
Reference Database	RefSeq
Reference Genome	GRCh37 (hg19)
Coverage	Selected 90 core genes related to solid tumors, including all coding regions of transcripts and UTR regions of selected genes.
Storage	-20℃±5℃
Sequence Platform	Illumina / MGI
Detection Range	Fusion, transcript variation, and expression, etc.
Recommend Sequencing Read Length	PE150
Recommend Sequencing Data	3 Gb
Applications	Adjuvant diagnosis, medication guidance, and prognostic indication

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Advantages

Comprehensive and precise

Designed to target and capture regions of interest across all transcripts, tailored for RNA-level samples.

Sensitive and efficient

Efficiently captures target regions, reduces costs, and enables sensitive detection.

Stable and superior

Leveraging iGeneTech® TargetSeq® probe hybridization capture sequencing technology, delivering stable and excellent performance.

Flexible customization

Offers customizable and semi-customizable services (e.g., probe densification, expanding target regions) based on client needs, meeting personalized requirements.

Performance

Excellent Performance

Capture performance testing

RNA reference material consistency and performance testing. Total RNA was extracted from Seraseq® FFPE fusion RNA Reference Material v4, and libraries were prepared using an RNA library preparation kit with a 50ng input amount. After hybridization capture, sequencing was performed on an Illumina NovaSeq 6000 platform with PE150 read length.

Fusion reference material validation

Fusion reference material detection results

Note: Comparison of fusion detection in positive reference standards analysis results show that under the conditions of the same data volume (~3 Gb) and different input amounts, all fusion events were detected, which is consistent with the expected results.

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Ordering Info

TargetSeq® Core Genes Fusion RNA Panel

Product Name	Set	Cat. No
TargetSeq® Core Genes Fusion RNA Panel	4 rxn	PH2000590
	24 rxn	PH2000595
	96 rxn	PH2000592

Resources

bed File

TargetSeq® Core Genes Fusion RNA Panel bed file
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Demo DataSet

TargetSeq® Core Genes Fusion RNA Panel demo data
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Flyer

Core Genes Fusion RNA Panel
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